Chronic Fatigue – Modern Life Disorder & Karnozin EXTRA

You must have felt tired, exhausted, or listless at least once in your life. No matter how much you rest and sleep, it’s not enough. You still feel tired. Fatigue does not go away, it does not stop. A large number of obligations and responsibilities, as well as the dynamics and increasing demands of the modern way of life greatly affect the quality and health of people. Therefore, chronic fatigue occurs, which occurs more and more often in a large number of people. How do you recognize if you are one of them?

Chronic Fatigue

Chronic fatigue is a complex and debilitating condition characterized by constant fatigue lasting at least six months. In medicine, it is also known as myalgic encephalomyelitis (ME) or systemic expression intolerance disease (SEID). It is more like chronic fatigue syndrome, which should be distinguished from chronic fatigue. The difference between the two is that chronic fatigue is a medical diagnosis. This is supported by the symptoms that can be used to determine the correct diagnosis. The following seven symptoms make up chronic fatigue syndrome:

  • sensitivity to light, 
  • headache, 
  • sensitivity of lymph nodes, 
  • fainting and dizziness, 
  • pain in muscles and joints, 
  • inability to concentrate, 
  • insomnia and forgetfulness. 

The set of all these seven symptoms constitutes chronic fatigue syndrome.

Causes of Chronic Fatigue

The exact cause of chronic fatigue is not known, but it is assumed to be a combination of several factors: genetics, environment, lifestyle, and disorders of the immune system. Common symptoms of chronic fatigue include profuse fatigue that does not go away with rest, malaise after certain exertion (worsened after exposure to mental and physical stimuli), reinvigorating sleep, cognitive difficulties (often described as brain fog), pain in muscles and joints, headaches and the sensitivity of the lymph nodes.

Diagnosing Chronic Fatigue

Establishing an accurate diagnosis of chronic fatigue is a real challenge, given that there are no specific laboratory tests or biomarker indicators that would confirm it. Thus, when making a diagnosis, doctors usually rely on the evaluation of symptoms and the medical history of the disease. But also to rule out other potential causes of chronic fatigue, through various tests.

In order to bring all this into balance, it is best to apply a multidisciplinary approach. Start from the first thing, which is certainly the most important, which is sleep. Man spends a third of his life sleeping. Sleep affects every aspect of us, physical and mental health, immune system, brain performance, cognitive functions, etc.

Supplementation as a Prevention of Chronic Fatigue

An extremely important thing that you should pay attention to is certainly the diet, which should be varied. With the appropriate intake of carbohydrates, fats, and proteins, you contribute to preserving your health and the body will have enough energy. If the diet is poor in important macro and micronutrients, the body starves more and more, and eventually exhaustion occurs. This is supported by the intake of refined sugars, processed foods, simple carbohydrates, saturated fats, and foods with a high glycemic index. All this contributes to your body feeling tired, exhausted, and without energy.

Also, nowadays there is more and more talk about the intestinal microbiota, which plays a major role in maintaining health. If there is any imbalance in the intestinal flora, it can manifest as chronic fatigue. Also, the third but no less important thing is physical activity. The World Health Organization recommends walking for 45 minutes a day. If you can’t set aside time for a walk every day, three times a week for an hour is certainly enough. The most commonly recommended are: running, cycling, swimming, whatever you can fit into your lifestyle. Physical activity raises the levels of serotonin, dopamine, endorphins, and various other opioids in the brain.

Proper Nutrition and Nutritional Supplements

Nutritional supplements and supplementation are one of the most important factors in solving chronic fatigue.

Vitamins, minerals, amino acids as well as probiotics can make a significant difference. Dipeptide carnosine consists of two amino acids L-histidine and β-alanine. It is a supplement that helps raise energy levels at the mitochondrial level. Carnosine is known to have a powerful effect on mitochondrial repair and function, which is really rare in supplementation. Mitochondria are known as small energy factories that produce most of the energy needed for cell functioning, through the process of oxidative phosphorylation. When mitochondria are weakened, they produce less energy and generate more reactive oxygen species (ROS), which lead to cellular damage and dysfunction. If they fail for any reason, Karnozin EXTRA is here to help them because it restores them the most.

Chronic Fatigue and Karnozin EXTRA

Carnosine is the subject of numerous studies due to its ability to support mitochondrial function while combating mitochondrial dysfunction. It achieves this through several mechanisms:

  • as an antioxidant, it neutralizes free oxygen radicals and reduces oxidative stress,
  • by chelating copper and zinc metals, it prevents them from participating in reactions that create harmful free radicals,
  • by preventing glycation and stabilizing the cell membrane.

Mitochondrial dysfunction can occur as a result of various factors: stress, aging, and certain diseases. In addition to L-carnosine, it also contains vitamin E, L-carnitine-tartrate, coenzyme Q10, blueberry fruit extract, and grape seed extract. The synergy of these ingredients will provide you with all the benefits.

Treatment of Chronic Fatigue or Chronic Fatigue Treatment

Treatment of chronic fatigue focuses on relieving symptoms and improving quality of life. And this would imply a multidisciplinary approach that includes a combination of drugs to reduce or completely stop certain symptoms. In addition, cognitive-behavioral therapy (CBT) for the psychological aspect of this disease, graded exercise therapy, or pacing therapy to gradually increase the level of physical activity.


It is important to note that chronic fatigue can vary widely in its severity and impact on the individual, and its course can be unpredictable. This condition affects people of all ages, genders, occupations, and backgrounds and can significantly disrupt daily functioning and quality of life. Since Carnosine EXTRA is a dietary supplement, it is important to consult your doctor or pharmacist before including this supplement in your daily routine. This is especially true if you have some chronic diseases or are on regular therapy. They will create a personalized supplement plan based on your specific condition.


Dr. med. Sabina Unji